The host at this IP address is obviously operated by cybercriminals. It is running a malware botnet controller which is being used to control infected computers (bots) around the globe using a trojan horse.
Malware botnet controller located at 195.133.45.121 on port 443:
$ telnet 195.133.45.121 443
Trying 195.133.45.121…
Connected to 195.133.45.121.
Escape character is ‘^]’
briums01.top. 600 IN A 195.133.45.121
kebalx02.top. 600 IN A 195.133.45.121