The host at this IP address is running a malware botnet controller which is being used to control infected computers (bots) around the globe using a trojan horse.
Loki botnet controller located at 66.29.151.252 on port 80 (using HTTP POST):
hXXp://66.29.151.252/~nextimageblog/picture.php
Referencing malware binaries (MD5 hash):
7b467054ca8f7e9692cd00419d0a1d40 — AV detection: 15 / 63 (23.81)