The host at this IP address is running a malware botnet controller which is being used to control infected computers (bots) around the globe using a trojan horse.
Loki botnet controller located at 104.21.78.45 on port 80 (using HTTP POST):
hXXp://bobreplace.xyz/five/fre.php
$ dig +short bobreplace.xyz
104.21.78.45
Referencing malware binaries (MD5 hash):
898badd240f8d99c109b1c8647eaa1f1 — AV detection: 8 / 66 (12.12)
Other malicious domain names hosted on this IP address:
hyundaijatim.com 104.21.78.45
bobreplace.xyz 104.21.78.45